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Clinical Relevance of Complex Chromosomal Aberrations

Author: Zuzana Zemanová, a kol.

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Cryptic translocation t(12;21)(p13;q22) which give origin to the ETV6/RUNX1 hybrid gene can be found by I-FISH in approximately 20-25% of children with B precursor ALL as the most frequent specific aberration. This translocation is generally associated with good outcome. Despite of its favorable prognostic value, late relapses may occur within this group of patients. 

Contribution of molecular cytogenetic analyses to diagnosis and treatment of malignant brain tumours
.. of patients according to specific chromosomal aberrations in tumour cells. For detection of.. .. of patients according to specific chromosomal aberrations in tumour cells. For detection of the most..

Occupational health risk assessment
.. of workers. Categorization of work is allowing complex evaluation of the factors load level of..

Serum bilirubin as a predictor of oxidative stress-mediated diseases
.. that the role of HO-1 in cancerogenesis is more complex and further studies of possible contributing..

SCHWARZ, Daniel, KOMENDA Martin, ŠNÁBL Ivo, DUŠEK Ladislav. A uniform platform for electronic publishing and sharing the educational content in the network of medical faculties MEFANET [online]. [cited 12. 06. 2025]. Available from WWWW: http://portal.med.muni.cz. ISSN 1801-6103. Version 2.2.0 [2021].

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